Blog, News and Events

We are revolutionizing the translational potential of animal models in preclinical research. Discover the latest articles and news about our recent activities.

Humanized Liver Models: Revolutionizing RNA Therapeutic Development

The rapid growth of RNA therapeutics, including siRNA and mRNA, is transforming the pharmaceutical and medical landscape, offering unprecedented potential for treating diseases ranging from viral infections to metabolic disorders. Despite this promise, translating these groundbreaking treatments from the lab to the clinic is fraught with challenges.

Topics icon PXB-mouse, News, Blog

Humanized Liver PXB-Mouse

Targeting cccDNA in Human Hepatocytes: Pathway to a Cure for HBV?

Globally, around 250 million people are infected with hepatitis B virus (HBV) and more than 1 million more are estimated to become infected yearly. Researching the HBV viral life cycle and identifying potential novel therapeutics is challenging as only human and chimpanzee hepatocytes are permissive to HBV. However, due to the cost and ethical restrictions, alternative models are being explored. In vivo, rodent models including humanized liver chimeric mice (for example PXB-mice) and the AAV-HBV mouse model are being utilized. While these models are useful, each has their own pitfalls.

Topics icon Blog, PXB-cells

Primary human hepatocytes on culture plate

Exhibition at AALSD - The Liver Meeting 2024

The 75th Liver Meeting organized by the American Association for Liver Disease (AASLD) is being held from November 15th to November 19th, 2024 at the San Diego Convention Center. PhoenixBio is excited to be sponsoring a booth and attending the The Liver Meeting in person in San Diego, California. Meet with our team at Booth #1831 to learn more about PhoenixBio's capabilities and how we can help you advance and deliver tomorrow’s technologies.

Topics icon Events

PhoenixBio AASLD TLM 2024

Exhibition at ESGCT 2024

Exciting Innovations Await at the 31st Annual Congress of the European Society of Gene and Cell Therapy. We are thrilled to announce that our company will be attending the 31st Annual Congress of the European Society of Gene and Cell Therapy (ESGCT) in Rome, Italy from October 22nd-25th, 2024. PhoenixBio is excited to be sponsoring a booth and attending the the annual meeting to get the latest updates in the fast moving field of gene and cell therapy! Meet with our team at Booth #B18 to learn more about PhoenixBio's capabilities and how our humanized liver mouse model and fresh human hepatocytes provide an unparalleled translational platform to advance your studies.

Topics icon Events

Attending HDV 2024

Join us at Delta Cure 2024 in Milan! We’re excited to announce that PhoenixBio will be attending the 3rd Edition of Delta Cure International Meeting in the beautiful city of Milan, Italy on October 11th to October 12th, 2024! This premier event is a fantastic opportunity for pharmaceutical professionals and innovators to gather and explore the latest advancements in viral hepatitis.

Topics icon Events

HDV Delta Cure Meeting 2024

Exhibition at OTS 2024

The 20th Annual Meeting of the Oligonucleotide Therapeutics Society will be held from October 6th - 9th in Montreal, Canada. PhoenixBio is excited to be sponsoring a booth and attending the the annual meeting to get the latest updates in the fast moving field of Oligonucleotides! Meet with our team at Booth #3-1 to learn more about PhoenixBio's capabilities and how our humanized liver mouse model and fresh human hepatocytes provide an unparalleled translational platform to advance your studies.

Topics icon Events

OTS 2024

Exhibition at the ISSX/JSSX 2024

The 26th North American ISSX and 39th JSSX joint meeting is empowering scientists through education. PhoenixBio is excited to be sponsoring a booth and attending the the 26th North American ISSX and 39th JSSX Meeting. This meeting will convene at the Hilton Hawaiian Village Waikiki Beach Resort September 15th-18th, 2024. Meet with our team at Booth #112 to learn more about PhoenixBio's capabilities and how we can help you deliver and evaluate the human safety of tomorrow’s therapeutics.

Topics icon Events

ISSX/JSSX 2024 PhoenixBio Booth

2024 International HBV Meeting

PhoenixBio is attending the International HBV Meeting in person in Chicago, Illinois on September 11th - 15th, 2024. Meet with our team to learn more about PhoenixBio's capabilities and how we can help you advance and deliver tomorrow’s viral hepatitis therapies.

Topics icon Events

HBV Meeting 2024

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